BDBM50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole
SMILES Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl
InChI Key InChIKey=CEUORZQYGODEFX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 50130293
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [3H]mesulergine from rat cerebral cortex 5HT2C receptor measured after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor in human tsA201 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Binding affinity to 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 76nMAssay Description:Displacement of [3H]Mesulergine from rat 5-HT2C receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 95nMAssay Description:Displacement of [3H]-LSD from 5HT2C receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scintillation cou...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 95nMAssay Description:Displacement of [3H]-LSD from 5HT2C receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scintillation cou...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Displacement of [3H]-Mesulergine from human 5-HT2C receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 250nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataIC50: 25.7nMAssay Description:(1) The prepared membrane was first applied with appropriate amount of homogenized liquid, and homogenizer was used for evenly dispersing. 15 tubes w...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.38E+3nMAssay Description:Antagonistic activity at 5-HT2c receptor (unknown origin) after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.38E+3nMAssay Description:Antagonistic activity at 5-HT2c receptor (unknown origin) after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.38E+3nMAssay Description:Antagonist activity at 5-HT2C receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assayMore data for this Ligand-Target Pair